Arbejde Postdoc for Establishment of In Vitro Systems for Peptide Analogue Drug-Drug Interaction Assessments unspecified Novo Nordisk A/S - jobtilbud
reference: 5004676
documentId: 5004676
connectionPointId: 7
lastModificationDate: 1560429021450
stillingsbetegnelse:
Postdoc for Establishment of In Vitro Systems for Peptide Analogue Drug-Drug Interaction Assessments
jobbeskrivelse:
Are you interested in working with one of the world’s most successful biopharmaceutical companies and with a top-ranked university? Do you want to be involved in contributing to Novo Nordisk global strategy of utilising in vitro systems for predicting drug-drug interactions for our peptide drug candidates? If so, you now have the opportunity to apply for a Postdoc project at Novo Nordisk and at the Centre for Applied Pharmacokinetic Research (CAPKR, https://www.capkr.manchester.ac.uk/), University of Manchester.
About the department
You will join the Global Discovery & Development Sciences in the Novo Nordisk R&D organisation. The position will be associated to the department of Development ADME which is responsible for the investigation and evaluation of drug-drug interactions for compounds in drug development. The experimental part of this project will primarily be conducted at CAPKR, University of Manchester under the supervision of principal investigator Dr. Aleksandra Galetin. Dr Galetin’s expertise is in mechanistic in vitro characterisation of hepatic and renal enzymes and transporters in different cell systems; PBPK/translational modelling of transporter kinetics and endogenous biomarkers for transporter-mediated drug-drug interactions (https://www.research.manchester.ac.uk/portal/aleksandra.galetin.html).
The position
Drug-drug interactions for therapeutic peptides is an evolving area with challenges regarding the optimal and relevant in vitro studies during the drug development phase. Project aims to evaluate potential drug-drug interaction risk via regulation of CYP enzymes and relevant transporters by peptide analogues. This project will give you the possibility to develop new competences and skills within in vitro cellular systems aiming to perform mechanistic evaluation of drug-drug interaction risk associated with peptide analogues. As part of the evaluation and validation of the in vitro data generated the project will aim to implement the in vitrofindings with therapeutic peptide in existing PBPK models for small molecule drugs to predict drug-drug interaction risk for likely co-medications in targeted patient population (e.g., obesity). This is a two-year postdoctoral position where the employment period will start at Novo Nordisk in Copenhagen, followed by a 1+ year relocation to University of Manchester before returning to Novo Nordisk, Copenhagen.
Qualifications
We are looking for a candidate that holds a Ph.D. in Drug metabolism, Pharmaceutical or Biomedical Sciences or a related discipline and who has laboratory-based experience with cellular in vitro systems and quantitative drug metabolism/transporters. Strong understanding of DMPK principles is highly desirable; experience with drug-drug interaction prediction and PBPK modelling will be an advantage. The ideal candidate should have demonstrated excellent scientific productivity, evidenced by high-quality research publications. As this project is based on a close collaboration between two research groups, you should be able to spend time in both Denmark and England and be interested in building relationships between the project members. The candidate is expected to maintain expertise in scientific developments relevant to the objectives of CAPKR and University of Manchester as appropriate. English at a professional level is required.
Contact
For further information, please contact Carolina Säll at +45 3077 6752
Deadline
June 30th 2019
Applications will be assessed on an ongoing basis; therefore, we encourage you to apply as soonas possible.
Millions rely on us
To work for Novo Nordisk you will need the skills, dedication and ambition to change lives for the better for millions of patients living with diabetes and other chronical diseases. In exchange, we offer the chance to be part of a truly global workplace, where passion and engagement are met with opportunities for professional and personal development.
numberOfPosts: 1
jobCategoriesCodes_0: http://data.europa.eu/esco/isco/C2310
abstractJV_contact_0: Please apply using one of the specified channels
positionTypeCode: directhire
contractTypeCodes_0: fulltime
Arbejdsgiver Navn: Novo Nordisk A/S
source: DK-STAR
Similiar jobtilbud
211-0017/18-2N Tenure-track Assistant Professor of Agricultural Economics -
Tenure-track assistant Professor of Agricultural Economics Department of Food and Resource Economics Faculty of Science University of Copenhagen The Department of Food and Resource Economics, Faculty of Science, University of Copenhagen invites applications for a position as assistant professor
KU - SCIENCE - IFRO - 2019-01-05 - unspecified
Antimicrobial R&D Scientist -
DuPont has a rich history of scientific discovery that has enabled countless innovations and today, we\'re looking for more people, in more places, to collaborate with us to make life the best that it can be.We are looking for an experienced scientist for a maternity cover for 12 months (potentially
DUPONT NUTRITION BIOSCIENCES APS - 2019-04-03 - unspecified
Autoforum søger Danmarks bedste mekaniker -
Vi har meget travlt, og derfor søger vi en mekaniker – gerne med erfaring inden for Citroen eller Peugeot PSA – Men det er ikke et krav. Du kommer til at indgå i et team med super dygtige kollegaer – som på nuværende tidspunkt tæller omkring 22 medarbejdere, hvoraf
AUTOFORUM MIDDELFART, P.M. AUTOMOBILER ApS - 2018-10-02 - unspecified
Career Opportunities: HSE Technical Manager (12746) -
Division Offshore Location: Denmark, Vejle Functional area: Health & Safety & Environment About Siemens Gamesa Renewable EnergyWith a worldwide installed capacity of 75 GW, Siemens Gamesa Renewable Energy has a presence in more than 90 countries and a team of 27,000 employees
Siemens Gamesa Renewable Energy A/S - 2018-11-23 - unspecified
C.C Rengøring søger fuldtidsmedarbejder til erhvervsrengøring -
Operaid ApS søger på vegne af C.C Rengøring en rengøringsassistent til 37 timers arbejde pr. uge.C.C Rengøring er en dansk familieejet virksomhed, som leverer professionel rengøring til erhverv, private, institutioner og boligforeninger. Vi leverer miljøvenlig rengøring til konkurrencedygtige
OPERAID ApS - 2018-12-22 - unspecified
Ccut i Ejstrupholm søger en frisør :-) -
Ccut i Ejstrupholm søger en frisør :-)Vi søger en smilende, udadvendt og dygtig frisør, som har lyst til at indgå i vores lille team. Vi er en anderledes og meget personlig salon med en afslappet atmosfære præget af hjemlig hygge og personlig stil.Her er kunden i centrum både før, under og efter
c cut v/carina madsen - 2019-05-01 - unspecified
Danmarks største trafikselskab søger studentermedhjælp til analyseopgaver -
Har du lyst til at blive en del af et team bestående af engagerede og fagligt stærke analytikere? Movia driver og udvikler den kollektive transport på Sjælland og de omkringliggende øer, herunder baseret på viden om passagertal, salgstal, kundeundersøgelser og mange andre datakilder. Som rådgivere
Trafikselskabet Movia - 2019-05-14 - unspecified
DDS SCADA Hardware Work Package Owner -
Sobre Siemens Gamesa Renewable Energy Siemens Gamesa Renewable Energy cuenta con una base instalada de 75 GW en todo el mundo, presencia en más de 90 países y un equipo de 27.000 empleados. Con presencia a lo largo de toda la cadena de valor, la compañía realiza desde el diseño y fabricación
Siemens Gamesa Renewable Energy A/S - 2019-03-02 - unspecified
Kommunikationsmedarbejder til at styrke samarbejdet mellem DTU og landets gymnasier -
Danmarks Tekniske Universitet søger en medarbejder til studenterrekrutteringsteamet i DTU\'s centrale kommunikationsenhed. Din opgave bliver at understøtte udviklingen af en ny ordning, hvor ph.d.-studerende fra DTU skal formidle viden om aktuel forskning og bæredygtig udvikling til gymnasieelever.
Danmarks Tekniske Universitet - 2019-05-08 - unspecified
Kontorassistent -
Kontorassistent Søges HN Rengøring søger en kontorassistent til vores kontor, som kan lidt af hvert – gerne med erfaring indenfor administrative opgaver. Intern: Behjælpelig med fakturering Behjælpelig med udarbejdelse af løn (kendskab til Proløn
HN Rengøring ApS - 2018-10-09 - unspecified
Lead Senior Specialist, Power Plants-18000245 -
Are you ready to drive products and technologies with focus of grid integration of Vestas Renewable Hybrid Power Plants? Do you have the experience and the interpersonal skills to act at the highest levels of product and technology development in a fast-moving business? Are you a technical
Vestas Wind System A/S - 2018-08-21 - unspecified
Linden søger en pædagog og en barselsvikar for pædagog -
Vi søger en pædagog på 31 timer pr. d. 1. november 2018 og en barselsvikar for pædagog 32 timer pr. 22. november 2018 Linden er en selvejende institution beliggende på indre Nørrebro. I Linden har vi en aldersopdelt gruppestruktur og børnetallet er ca. 82
MENIGHEDSBØRNEHAVEN LINDEN V/HELLIGKORS KIRKEN - 2018-10-02 - unspecified
Mechanical Engineer - R&D Front Office, Odense, Denmark -
Do you want to be part of a fast-growing, successful and market-leading robotics company, where nothing is impossible?We are looking for a team player with drive and passion. You must be proactive and open about your work and have a collaborative mindset. Together, we are finding innovative solutions
UNIVERSAL ROBOTS A/S - 2018-11-29 - unspecified
NÆSTVED ; Revisorer med lyst til at arbejde med opgaver fra A-Z inklusiv kundekontakt– i uformelt miljø med en dejlig fornuftig balance ml. arbejdsliv- og privatliv -
Område: Vi søger for vores kunde, Kvalitetsrevision i Næstved, igen revisorer som brænder efter at få lov til at arbejde med opgaver fra A-Z. Firmaet er beliggende med fantastisk udsigt over Næstved Havn. Der er parkeringsfaciliteter lige ved kontoret og der er 15
Jobmægleren ApS - 2018-10-16 - unspecified
NPD Project Manager, Core Beer -
NPD Project Manager - Carlsberg, Carlsberg Denmark Do you like to make a difference with what you do? Do you like to lead a team of experts through a high impact project? Can you manage complex processes with many stakeholders? Can you keep attention to detail without losing sight of the big picture?
CARLSBERG BREWERIES A/S - 2018-10-04 - unspecified
One ERP Transportation Management Consultant -
Job DescriptionDanfoss is looking for a Transportation Management Consultant for our One ERP project responsible for driving implementation of Transportation Management system provided by Descartes. You will be working in the Transportation Management Team, a part of the Logistics teams in the
DANFOSS A/S - 2019-02-26 - unspecified
Postdoc in Protein Science -
A 2-year postdoctoral fellowship is available at Department of Biotechnology and Biomedicine (DTU Bioengineering), the Technical University of Denmark. The position will be placed in the Enzyme and Protein Chemistry group in the section of Protein Chemistry and Enzyme Technology with about 70 staff members.
Danmarks Tekniske Universitet - 2019-01-23 - unspecified
Produktionsmedarbejder -
Lacuna A/S er en danskejet virksomhed, der udvikler, fremstiller og sælger facade foldedøre i ind- og udland. Se mere på http://www.lacuna.dk Vi er i rivende udvikling og søger nu en dygtig produktionsmedarbejder. Lacuna er kendt for høj kvalitet og finish og ønsker derfor
LACUNA A/S - 2019-04-26 - unspecified
Reliability Engineer – Large Green Field Project -
General Services, Industrial Projects, Information Systems, Operations/Exploitation, Secretarial/Administrative Support, Strategy Economics BusinessESBJERG ONSHORE(DNK)DenmarkJob DescriptionAre you interested in taking part of the redevelopment of the existing Tyra field? And, would you like to provide
Total E&P Danmark A/S - 2019-02-16 - unspecified
Salgsassistent med afdelingsansvar -
Vi søger en serviceminded og arbejdsom person der er klar til udfordringer og personlig udvikling.Vi forventer du er selvstændig, engageret og arbejdsom. Du skal være klar på at samarbejde, blive en del af personaleholdet og bidrage positivt til alle kollegaer.Du skal være uddannet indenfor dagligvarer
ABC LAVPRIS, HERNING ApS - 2019-05-07 - unspecified
Senior Director, Sustainable Materials Strategy & Innovation -
Are you passionate about sustainability and delivering strategic leadership across the full value chain?As part of the amazing Environmental Responsibility team you bring your leadership experience in to play and help shape the strategic direction for LEGO sustainable materials.Core Responsibilities•
LEGO SYSTEM A/S - 2019-03-07 - unspecified
Senior Project Manager - CRM Delivery -
Job Description Do you enjoy working with project plans in a structured manner, and do you want to be a key player in the global implementation of new functionalities, tools and customer relationship management solutions? Do you take pride in ensuring that implemented solutions are always running in
DANFOSS A/S - 2018-09-15 - unspecified
Service technician/engineer -
EIVA is an engineering company operating in the international maritime industry. We offer hardware, software and rental, maintenance and training services to customers specialising in offshore wind, construction, and oil and gas, just to name a few fields we are active in. Consequently, there is a lot
EIVA A/S - 2019-01-25 - unspecified
Serviceminded renovationsarbejdere søges -
NordRen A/S søger servicemindede og gerne erfarne renovationsarbejdere til ansættelse pr. 1/10-2018. Der er tale om 3 faste stillinger, samt et antal afløserstillinger i en attraktiv og nystartet virksomhed i Danmark. Den primære arbejdsopgave er indsamling af dagrenovation
NordRen Denmark A/S - 2018-09-12 - unspecified
Søger frisk bager til til fuldtidsarbejde (Nat arbejde) / Looking for a fresh baker for full time work. (Nightwork) -
Hej, vi her i center bageren, Brøndby strand søger en uddannet bager. Arbejde foregår om natten, og vi er klar til at tage imod dig med det samme. Du kommer ikke til at arbejde alene, men tiderne kan svinge en gang imellem, derfor er det vigtigt at du er en holdspiller, og er villig
Center Bageren v/Read Ahmad Hasan Alsbaihi - 2018-09-07 - unspecified
Student Assistant for Process Modelling and Simulation & Distillation -
Are you a highly motivated student who has interest in process simulation? Are you eager to apply theory to practice and directly have influence on process improvement and optimisation? If so, we offer a challenging and fun student position in Utility and Solvents (US) support, Kalundborg.About the departmentYou
Novo Nordisk A/S - 2018-08-01 - unspecified
Super søde familie i gentofte søger hjælp 4 - 5 gange om ugen til at hente deres barn på 18 måneder -
Har du erfaring med at passe børn i alderen 18 måneder og bor du i Gentofte?Kan du hente i vuggestuen ved Vangede st. senest kl 16.00 4 - 5 gange om ugen? Familien bor ved Gentoftegade og søger en stabil hjælp til at hente eftermiddage. Jobbet er perfekt for dig som ønsker lidt ekstra timer.
Rexkyoo ApS - 2019-06-10 - unspecified
Sygeplejerske-, bioanalytiker-, medicin- eller jordemoderstuderende søges. -
Vi søger en ny medarbejder, til at varetage inseminationer, ultralydsscanninger, akupunktur, arbejder i laboratoriet, samt svare mails, telefonopkald og mange andre spændende ting her på fertilitetsklinikken. Vi leder efter en person som er fleksibel, omsorgsfuld, imødekommende
SELLMER KLINIK ApS - 2018-07-30 - unspecified
Variant Configuration Consultant -
Job DescriptionDoes becoming a team member of an international team developing innovative solutions based on SAP Variant Configuration LO-VC appeal to you? And are you motivated by ensuring configurator operations, supporting the organization in configurator questions and last but not least documenting
Danfoss A/S - 2019-01-15 - unspecified
Versatile employee wanted for construction work -
Skilled and versatile employee with experience in construction wanted. You need to be able to work independently and finish the jobs you start properly with an eye for detail. You have to be a tidy person and be willing to do cleaning and tidying in the workspace - both after yourself and others. You
STAUT EJENDOMSMÆGLER ANDERS LINNET - 2019-05-21 - unspecified
