Arbejde Senior Research Scientist in Paediatric Oncology Bioinformatics Hovedstaden Danmarks Tekniske Universitet - jobtilbud

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stillingsbetegnelse:
Senior Research Scientist in Paediatric Oncology Bioinformatics

jobbeskrivelse:
An experienced bioinformatician is sought in the translational oncology space with a focus on germline predispositions to aetiology, tumour biology, and treatment response. The position is shared between the Technical University of Denmark (DTU) and Copenhagen University Hospital - Rigshospitalet (RH). The position will lead data analyses and pipelines across a wide variety of patient data including clinical, epidemiological, genomics, metabolomics, and metagenomics spaces, guiding interventional functional and clinical research. The Center for Biological Sequence Analysis (CBS, http://www.cbs.dtu.dk) at DTU is one of the largest bioinformatics and systems biology clusters in Europe with more than 110 employees. CBS has strong expertise in network biology, machine learning and in data integration, including human variation data as well as data on drugs, environmental chemicals and nutrients. The Center has created many original data integration and biological prediction approaches. Health and Big Data approaches are areas of active interest. The Pediatric Oncology Research Laboratory at Rigshospitalet (BONKO lab) is one of the largest childhood cancer research units in the Nordic/Baltic region with more than 60 part-time or fulltime employees. It primarily addresses childhood leukemia, but also pursues childhood cancer etiology, epidemiology, survival and late effects in general. Responsibilities and tasks Description of the content of the position in relation to: -The candidate is expected to oversee and run the computational parts of a whole genome sequencing pipeline for nationwide screening of childhood oncology patients in a diagnostic setting. He/she will also be driving data analyses in the underlying research group working with germline predispositions towards childhood leukaemia aetiology, biology, and drug disposition and response. -The role will involve data integration and machine learning across genomic, transcriptomic, clinical, epidemiological data and prior biological knowledge. It is expected in the future to also include metagenomic and metabolomic data. -The candidate will supervise, coordinate, and train junior researchers within the field. The coordination role will also include our emerging industrial collaborations. The position will be based at the Technical University of Denmark in the Functional Human Variation group headed by Associate Professor Ramneek Gupta, in close collaboration with Professor MD Kjeld Schmiegelow at the Department of Paediatrics and Adolescent Medicine, Rigshospitalet. Other content of the position: -It is expected that the candidate will use his experience for actively contributing to research based teaching programmes, as well as participating in grant writing for growing activities in the area. -As WGS becomes mainstream in the clinic, the candidate will participate in ethical/social discussions and technical coordination of large data pipelines across multiple geographical sites. Qualifications Candidates must -hold a PhD degree or equivalent as well as academic qualifications equivalent to those obtained by holding a position as Researcher or Postdoc. Further qualifications: Applicants should hold a PhD in bioinformatics, biology, engineering, computer science or similar, with 2-5 years of postdoctoral experience. The candidate must have strong computational skills and prior experience with large data sets, Unix command line environments, as well as either Perl, Python or a comparable scripting language. R and relational database skills are considered a strength, as is experience with application of statistics, systems biology, machine learning and multi-omics data integration methods. A strong background in biology is a prerequisite, preferably with experience in oncology. Strong communication skills, participating in academic assessment work and the ability to interface across multiple disciplines are required, as well as the ability to work through several priorities. Th

Arbejdsgiver Navn: Danmarks Tekniske Universitet

Arbejdsgiver telefonnummer: 45252525

Arbejdsgiver faxnummer: 45881799

Job kort beskrivelse:
Undervisning og forskning på universiteter og højere læreranstalter

land: Danmark

region: Hovedstaden

Kontrakt varighed: Fast

Kontrakttype: Fuldtid

krævede uddannelse: Ikke angivet

Kilde til jobtilbud: AMS, Offentlige arbejdsformidlinger, Danmark

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