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reference: 4973687

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lastModificationDate: 1554899419570

stillingsbetegnelse:
Research assistant in Sensor Development for Lateral Flow Assay for specific Bacterial Infections

jobbeskrivelse:

The Nano Bio Integrated Systems group at DTU Bioengineering (NaBIS) is an interdisciplinary group specializing in application-driven research within the fields of biotechnology and environmental monitoring. The group's vision is to integrate micro- and nanoscience in lab-on-a-chip systems with the aim of developing novel technologies for biological analysis, medical diagnosis, treatment monitoring as well as environmental monitoring. The group currently consists of 12 postgraduate and senior members and 4 master students.

We offer a research assistant position for 25 month within the field of lateral flow assay development. The sensor will be used in order diagnose infection in wounds, including which bacteria are responsible and the concentration thereof.

Responsibilities and tasks

The position concerns the development of a paper-based biosensor for the detection and quantification of several strains of bacteria in serum. We are focusing on colorimetric detection, where the intensity of the light will give an indication of the concentration of the bacteria in the sample. The sensor will need to identify 3-6 different bacteria. A standalone device will scan the sensor and automatically record the presence or not of bacteria as well as report a concentration. The project is a collaborative effort between biologists, biomedical, nanotechnology, computer engineers, business developers and doctors.

You will be responsible for developing the bioassay, including investigating binding efficiency, concentration limits and shelf life. You will be involved in the development of the sensor This includes, but is not limited to, increasing sensor sensitivity, optimising geometry and fabricationg sensor for field testing. You will be working in close collaboration with a nanotechnologist and a computer scientist.

• Your main responsibility will be to develop the bioassay on the sensor
• You will also be collaborating with the two other scientist for the fabrication of the sensor and its integration with the rest of the components (electronics).

Together with the rest of the project team you will also be involved in:

• Establishing the sensitivity and specificity of the assays on the sensor material
• Testing the sensor on clean bacteria samples, spiked laboratory samples and real samples in the field

Qualifications

Candidates should have a master degree in the field of Biology, Biotechnology or equivalent.

• You have large experience with Bioassay development and testing
• You have experience with ELISA testing
• Experience within colorimetric sensors will be preferable.
• You are able to follow, execute and revise biological protocols
• Some experience with paper microfluidics is welcomed, but not necessary
• Basic sensor engineering is welcome, but not necessary.
• Experience with phage display is welcome, but not necessary.
• You enjoy working with complex topics
• You are focused on the process as well as the outcome
• You are motivated to work in interdisciplinary teams working towards a common goal

Flexibility and self-motivation are desired skills at DTU. In addition, we expect you to be interested in collaboration and take personal responsibility for your work.

We offer

DTU is a leading technical university globally recognized for the excellence of its research, education, innovation and scientific advice. We offer a rewarding and challenging job in an international environment. We strive for academic excellence in an environment characterized by collegial respect and academic freedom tempered by responsibility.

Salary and terms of employment

The appointment will be based on the collective agreement with the Danish Confederation of Professional Associations. The allowance will be agreed upon with the relevant union.

The period of employment is 25 months, start date as soon as possible.

You can read more about career paths at DTU here. http://www.dtu.dk/english/about/job-and-career/working-at-dtu/career-paths

Further information

Further information may be obtained from Winnie E. Svendsen, +45 3125 9369, e-mail: wisv (at) dtu.dk

You can read more about DTU Bioengineering at www.bioengineering.dtu.dk http://www.bioengineering.dtu.dk

Application procedure

Please submit your online application no later than 24 April 2019 (local time).

To apply, please open the link "Apply online", fill out the online application form. The following must be attached in English:

• Application (cover letter)
• CV
• Diploma (MSc/PhD)
• List of publications

Applications and enclosures received after the deadline will not be considered.

All interested candidates irrespective of age, gender, disability, race, religion or ethnic background are encouraged to apply.

Department of Biotechnology and Biomedicine (DTU Bioengineering) is an international leader in biotechnology and biomedicine. Our engineering approach to all aspects of biotechnology and biomedicine positions us as a valuable player with unique competences in a growing bio-based economy and with health systems transforming towards personalized medicine. We have a clear focus on the needs in the life science industry and point towards innovation, new businesses and scientific services for the benefit of society. The department has extensive collaborations with national and international research units and industry. DTU Bioengineering has approx. 210 employees, of which 2/3 is scientific staff. The department is located at DTU Lyngby Campus.

DTU is a technical university providing internationally leading research, education, innovation and scientific advice. Our staff of 6,000 advance science and technology to create innovative solutions that meet the demands of society, and our 11,200 students are being educated to address the technological challenges of the future. DTU is an independent academic university collaborating globally with business, industry, government and public agencies.


numberOfPosts: 1

jobCategoriesCodes_0: http://data.europa.eu/esco/isco/C2310

abstractJV_contact_0: Please apply using one of the specified channels

positionTypeCode: directhire

contractTypeCodes_0: fulltime

Arbejdsgiver Navn: Danmarks Tekniske Universitet

source: DK-STAR