Arbejde PhD position in Auto-Sampling and Monitoring of Bioprocesses Hovedstaden Danmarks Tekniske Universitet - jobtilbud

GÆLDER
stillingsbetegnelse:
PhD position in Auto-Sampling and Monitoring of Bioprocesses

jobbeskrivelse:
A PhD position is available at the Department of Chemical and Biochemical Engineering, Technical University of Denmark (DTU). The project is focusing on testing and validation of a new automatic sampling concept in addition to investigating the potential of real-time monitoring of bioprocesses with HPLC, different spectroscopic methods (e.g. NMR, Raman, fluorescence) and flow cytometry. One of the primary objectives of industrial bioprocess research and development is the establishment of economically viable processes through increasing product yields and reduced operating cost. However, particular fermentations provide a demanding environment for reliable, stable and noise-free measurement and the measurements must provide demonstrable benefits without compromising the process. As a consequence fermentation production reactors are normally rather sparsely instrumented and typically only involve standard sensors such as pH, temperature and dissolved oxygen. Furthermore, robust, automatic sampling systems which also include a sampling preparation part enabling real-time analysis by more advanced methods like flow cytometry and NMR are not available on the market today. The goal of the current project is to understand the relationship between measured variables and process quality parameters and achieve real-time measurements of these process relevant parameters that facilitate monitoring and control. The project will be part of BIOPRO, which is a partnership between industry and university on Zealand aiming to create a world-class biotech cluster and committed to finding new ways of making biotech production more competitive and sustainable through applied research. Responsibilities and tasks The candidate will be responsible for validating a prototype for automatic sampling including a sample preparation unit. The equipment will be applied on different selected bioprocesses such as pectin extraction and fermentation processes and will involve testing in pilot-scale and potentially also a full-scale test at a BIOPRO industry partner site. The candidate will be responsible for execution of different aspects of the project including both experimental work and data analysis. Qualifications Candidates should have a master's degree in engineering or a similar degree with an academic level equivalent to the master's degree in engineering. Previous experience with running fermentations and genuine knowledge within microbial physiology are essential. Experience with spectroscopic methods, flow cytometry, HPLC and with multivariate data analysis will be an advantage. Applicants must have analytical skills and the ability to work independently towards applied research goals. Furthermore, fluency in speaking, reading and writing English is required. Approval and Enrolment The scholarships for the PhD degree are subject to academic approval, and the candidates will be enrolled in one of the general degree programmes of DTU. For information about the general requirements for enrolment and the general planning of the scholarship studies, please see the DTU PhD Guide. Assessment The assessment of the applicants will be made by Associate Professor Anna Eliasson Lantz and Professor Krist V Gernaey. We offer We offer an interesting and challenging job in an international environment focusing on education, research, public-sector consultancy and innovation, which contribute to enhancing the economy and improving social welfare. We strive for academic excellence, collegial respect and freedom tempered by responsibility. The Technical University of Denmark (DTU) is a leading technical university in northern Europe and benchmarks with the best universities in the World. Salary and appointment terms The salary and appointment terms are consistent with the current rules for PhD degree students. The period of employment is 3 years. Expected starting date: December 2015. Further information Further information may be obtained from Associate Professor An

Arbejdsgiver Navn: Danmarks Tekniske Universitet

Arbejdsgiver telefonnummer: 45252525

Arbejdsgiver faxnummer: 45881799

Job kort beskrivelse:
Undervisning og forskning på universiteter og højere læreranstalter

land: Danmark

region: Hovedstaden

krævede uddannelse: Ikke angivet

Kilde til jobtilbud: AMS, Offentlige arbejdsformidlinger, Danmark

GÆLDER

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