Arbejde PhD position: Persistology and Survival of Listeria Monocytogenes in the Food Processing Environment Hovedstaden Danmarks Tekniske Universitet - jobtilbud

GÆLDER
stillingsbetegnelse:
PhD position: Persistology and Survival of Listeria Monocytogenes in the Food Processing Environment

jobbeskrivelse:
The Division for Microbiology and Production at the National Food Institute (DTU Food, http://www.food.dtu.dk) invites applications for a PhD position in the field of microbial food safety and hygiene with specific focus on the survival and persistence (“persistology”) of Listeria monocytogenes. The incumbent candidate will be based in an active research group that works broadly with microbial food safety and environmental hygiene using a wide specter of experimental approaches and techniques in state of the art laboratories. Background Listeria monocytogenes is a cold-tolerant pathogenic bacterium capable of causing serious disease in susceptible individuals including the very old, young, pregnant women and people with underlying immunological issues. L. monocytogenes remains a serious problem for the food industry, where the bacterium is able to survive and persist in spite of cleaning and sanitation efforts. Consequently, foods contaminated with L. monocytogenes continue to cause large outbreaks and financial losses for the affected industry. Clearly research is needed to identify better strategies that would allow the industry to obtain control with the organism. This project will investigate molecular mechanisms hypothesized to promote survival of the bacterium in the harsh production environment with its low temperatures, sanitation, biofilms and fluctuating humidity. This PhD project will apply microbiological and molecular biology techniques, and bioinformatics to elucidate the mechanisms applied by the organism in order to survive food processing stresses for the purpose of devising improved mitigation strategies. Responsibilities and tasks This PhD project will look at gene expression in the bacterium during exposure to food processing related stresses and explore if such stresses foster the development of a resistant mutant subpopulation or entry into a viable but nonculturable state. The detection and implications of putative persister L. monocytogenes on the safety of our food supply will be evaluated. Qualifications The candidate should be a motivated scientist with relevant experience and a master’s degree in Food Science and Technology, Microbiology, Biotechnology or related disciplines, with a strong background in microbiology and molecular biology. Experience with microbial culture techniques, handling of class 2 pathogens, extraction of nucleic acids, PCR, microscopy, protocol trouble-shooting and basic bioinformatics will be considered an asset. The candidate should demonstrate evidence of self-driven and independent research productivity, excellent collaboration and communication skills, and a strong motivation to succeed within a competitive research field. Approval and Enrolment The PhD scholarship is subjected to academic approval, and the candidates will be enrolled in one of the degree programs of DTU. For information about the general requirements for enrolment and the general planning of the scholarship studies, please see the DTU PhD Guide. Assessment The assessment of the applicants will be made by an assessment committee chaired by Professor Lisbeth Truelstrup Hansen. All applications will be reviewed to generate a short list of candidates. Potential candidates will be contacted for interview. We offer We offer an exciting and challenging job in an international environment focusing on education, research and innovation. There are good possibilities for professional and personal growth. The Technical University of Denmark (DTU) is a leading technical university in northern Europe and benchmarks with the best universities in the world. Salary and appointment terms The salary and appointment terms of the PhD position are consistent with the current rules for PhD degree students. The period of employment is 3 years. The position will be based at the DTU Mørkhøj Campus until Spring 2017 where the department will move to the main DTU campus in Lyngby, Denmark. Further information F

Arbejdsgiver Navn: Danmarks Tekniske Universitet

Arbejdsgiver telefonnummer: 45252525

Arbejdsgiver faxnummer: 45881799

Job kort beskrivelse:
Undervisning og forskning på universiteter og højere læreranstalter

land: Danmark

region: Hovedstaden

krævede uddannelse: Ikke angivet

Kilde til jobtilbud: AMS, Offentlige arbejdsformidlinger, Danmark

GÆLDER

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