stillingsbetegnelse: ADME Scientist

jobbeskrivelse:
- Research Scientist - Denmark - Måløv Do you want to use your experience within DMPK to be an integral part of the development of new therapies for the treatment of diabetes, obesity, growth disorder and haemostasis? Then come and join our department, Development DMPK - ADME. About the department We are a highly motivated and expanding department striving to provide and integrate state-of-the-art non-clinical and clinical Drug Metabolism and Pharmacokinetics data from late-stage discovery and throughout non-clinical and clinical development. Together with other departments in Non-Clinical Development we prepare for and contribute to non-clinical and clinical testing of new drug candidates. For projects in clinical development we are closely collaborating with clinical pharmacologists, statisticians and medical directors to optimise the DMPK characterisation. The ADME department consists of 6 scientists and 4 laboratory technicians working together in an open, challenging and cross-functional environment. The ADME department is a part of Development DMPK that also comprises a PKPD department. The job You will prepare scientific strategies and design, conduct and report on absorption, distribution, metabolism and excretion studies on new therapeutic candidates (modified peptides and proteins) in a GLP/GCP compliant facility. Collaboration with a variety of internal stakeholders in the R&D organisation as well as with Contract Research Organisations will be an integral part of your work. As part of interdisciplinary non-clinical and clinical project teams you will be responsible for delivering, interpreting and presenting ADME data according to project timelines and provide input to regulatory documents. This position will give you an opportunity to work with a number of different techniques, methods and studies within the ADME scientific field. Qualifications A Master or Ph.D. degree in a DMPK-related field followed by at least 6 years of relevant experience from academia or the pharmaceutical industry. Hands-on experience with some of the following techniques will be preferred: HPLC/UPLC, radio detection (3H and 14C), plasma protein binding (e.g. using Biacore), LC-MS, metabolite ID, drug-drug interactions and hepatocyte assays. Experience with GLP/GCP will be an advantage. Ideally, you should be familiar with the overall Drug Development process to facilitate interaction with both Early Discovery departments as well as clinical functions. We expect you to be ambitious, self-motivated and to have the ability to maintain the overview of many simultaneous tasks. Excellent scientific and collaborative skills are required. At Novo Nordisk, your skills, dedication and ambition help us change lives for the better. In exchange, we offer you an opportunity to work with extraordinary talent and benefit from a range of possibilities for professional and personal development. Contact For further information, please contact Mette Lund Pedersen +45 3079 6419 or Mette Finderup Grove +45 3079 5228. Deadline 5 August 2015.

Arbejdsgiver Navn: Novo Nordisk A/S

Arbejdsgiver telefonnummer: 44448888

Arbejdsgiver faxnummer: 44442314

Job kort beskrivelse:
Undervisning og forskning på universiteter og højere læreranstalter

land: Danmark

region: Hovedstaden

Kontrakt varighed: Fast

Kontrakttype: Fuldtid

krævede uddannelse: Ikke angivet

Kilde til jobtilbud: AMS, Offentlige arbejdsformidlinger, Danmark